Wearable artificial pancreas

Details Wearable artificial pancreas Wearable artificial pancreas

1990-05-22

1993-01-05

Pellegrino, Stephen C.

Surgery

Means for introducing or removing material from body for...

Treating material introduced into or removed from body...

604 65, 128635, A61M 3100

Patent

active

051766329

ABSTRACT:
A device for the continuous quantitative determination of glucose in the blood of a diabetic patient over a period of 24-36 hours, comprises a container for a saline solution with heparin, a microdialyzing needle inserted into a vein of a diabetic patient, a pump for injecting the solution into the microdialyzing needle, a semipermeable hollow fiber membrane located externally of the needle whereby dialysis occurs between the blood and the solution and only glucose and other substances of low molecular weight below 100,000 daltons go through the membrane and the concentration of the glucose and other substances of low molecular weight below 100,000 daltons inside the needle is proportional to that of the external side of the membrane. The needle is provided with an outgoing conduit, the conduit leads to a sensor, which comprises an enzymatic membrane coupled with a Platinum-Silver electrode. The glucose goes into the conduit, oxidation of glucose to gluconic acid and hydrogen peroxide occurs and the hydrogen peroxide is decomposed to give H.sub.2 O and oxygen with the liberation of two electrons whereby electric current is produced and the concentration of glucose in the blood is determined by determining the amount of current produced.

REFERENCES:
patent: 3512517 (1970-05-01), Kadish et al.
patent: 4240438 (1980-12-01), Updike et al.
patent: 4245634 (1981-01-01), Albisser et al.
patent: 4253456 (1981-03-01), Schindler et al.
patent: 4458686 (1984-07-01), Clark, Jr.
patent: 4467811 (1984-08-01), Clark, Jr.
patent: 4515584 (1985-05-01), Abe et al.
patent: 4526569 (1985-07-01), Bernardi
patent: 4633878 (1987-01-01), Bombardieri
patent: 4671288 (1987-06-01), Gough
patent: 4680268 (1987-07-01), Clark, Jr.
patent: 4711245 (1987-12-01), Higgins et al.
patent: 4721677 (1988-01-01), Clark, Jr.
patent: 4726381 (1988-02-01), Jones
patent: 4830011 (1989-05-01), Lim
patent: 4854322 (1989-08-01), Ash et al.
patent: 4953552 (1990-09-01), DeMarzo
patent: 5002661 (1991-03-01), Chick et al.
Rigaud et al. "Manual L.sup.+ Lactate Analyzer" 9th Annual Conference of the IEEE Engineering in Med. & Biology, 1987.

Affiliated with

Also associated with

Rating

Wearable artificial pancreas does not yet have a rating. At this time, there are no reviews or comments for this patent.

If you have personal experience with Wearable artificial pancreas, we encourage you to share that experience with our LandOfFree.com community. Your opinion is very important and Wearable artificial pancreas will most certainly appreciate the feedback.

Rate now

Comments { 0 }

Profile ID: LFUS-PAI-O-2388433