Plastic and nonmetallic article shaping or treating: processes – With step of cooling to a temperature of zero degrees c. or...
Reexamination Certificate
2007-10-16
2007-10-16
Johnson, Christina (Department: 1732)
Plastic and nonmetallic article shaping or treating: processes
With step of cooling to a temperature of zero degrees c. or...
C264S425000, C264S488000, C264S478000
Reexamination Certificate
active
10832852
ABSTRACT:
A wear resistant hydrogel for use as a prosthetic implant, such as for cartilage, is made by forming a solution of polyvinyl alcohol in a solvent of DMSO/water. The solution is placed in a mold and is gelated by cycling the mold in a freeze-thaw cycle at a temperature at or below 4° C. for a period of 2 to 24 hours. The hydrogel so formed is washed in a saline solution, including potassium carbonate. The hydrogel is then dehydrated to 20 to 70% water content and thereafter irradiated with Gamma radiation. The surface of the hydrogel is then cross-linked using a boric acid solution preferably between 2.5 and 5% for about 1 minute. The hydrogel is then rinsed and sterilized.
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DeMaria Christopher
Ngo Chau
Williams, III Philip F.
Howmedica Osteonics Corp.
Johnson Christina
Lerner David Littenberg Krumholz & Mentlik LLP
Sanders Janis
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