Wear resistant hydrogel for bearing applications

Plastic and nonmetallic article shaping or treating: processes – With step of cooling to a temperature of zero degrees c. or...

Reexamination Certificate

Rate now

  [ 0.00 ] – not rated yet Voters 0   Comments 0

Details

C264S425000, C264S488000, C264S478000

Reexamination Certificate

active

10832852

ABSTRACT:
A wear resistant hydrogel for use as a prosthetic implant, such as for cartilage, is made by forming a solution of polyvinyl alcohol in a solvent of DMSO/water. The solution is placed in a mold and is gelated by cycling the mold in a freeze-thaw cycle at a temperature at or below 4° C. for a period of 2 to 24 hours. The hydrogel so formed is washed in a saline solution, including potassium carbonate. The hydrogel is then dehydrated to 20 to 70% water content and thereafter irradiated with Gamma radiation. The surface of the hydrogel is then cross-linked using a boric acid solution preferably between 2.5 and 5% for about 1 minute. The hydrogel is then rinsed and sterilized.

REFERENCES:
patent: 3867728 (1975-02-01), Stubstad et al.
patent: 3875595 (1975-04-01), Froning
patent: 4309777 (1982-01-01), Patil
patent: 4334193 (1982-06-01), Gordy et al.
patent: 4349921 (1982-09-01), Kuntz
patent: 4663358 (1987-05-01), Hyon et al.
patent: 4664857 (1987-05-01), Nambu
patent: 4714469 (1987-12-01), Kenna
patent: 4734097 (1988-03-01), Tanabe et al.
patent: 4772287 (1988-09-01), Ray et al.
patent: 4904260 (1990-02-01), Ray et al.
patent: 4911718 (1990-03-01), Lee et al.
patent: 4988761 (1991-01-01), Ikada et al.
patent: 5007934 (1991-04-01), Stone
patent: 5012503 (1991-04-01), Nambu et al.
patent: 5047055 (1991-09-01), Bao et al.
patent: 5192326 (1993-03-01), Bao et al.
patent: 5534028 (1996-07-01), Bao et al.
patent: 5705780 (1998-01-01), Bao
patent: 5976186 (1999-11-01), Bao et al.
patent: 5981826 (1999-11-01), Ku et al.
patent: 6060534 (2000-05-01), Ronan et al.
patent: 6187048 (2001-02-01), Milner et al.
patent: 6264695 (2001-07-01), Stoy
patent: 6268405 (2001-07-01), Yao et al.
patent: 6280475 (2001-08-01), Bao et al.
patent: 6414214 (2002-07-01), Engelhardt et al.
patent: 6783721 (2004-08-01), Higham et al.
patent: 7098463 (2006-08-01), Adamovics
patent: 2003/0080465 (2003-05-01), Higham et al.
Yamaura K et al, Properties of Gels Obtained by Freezing/Thawing of Pol(vinyl Alcohol)/Water/Dimethyl Sulfoxide Solutions, 1989, J Appl Poly Sci, vol. 37, p. 2709-2718.
Kobayashi M, A study of polyvinyl alcohol-hydrogel (PVA-H) artificial meniscus in vivo, 2004, BioMed Mater Eng, vol. 14, p. 505-515.
Zheng-Qiu G et al, The development of artificial articular cartilage—PVA-hydrogel, 1998, BioMed Mater Eng, vol. 8, p. 75-81.
Purss H K et al, Poly(vinyl alcohol) hydrogels: Their synthesis and steps towards control of electroendosmosis, 2003, Electrophoresis, vol. 24, p. 12-19.
Structure and Properties of Poly (vinyl alcohol)-Iodine Complex Formed in the Crystal Phase of Poly (vinyl alcohol) Films, Y. Choi and K. Miyasaka, Journal of Applied Polymer Sciences, vol. 51, 613-618 (1994).
Hydrogels and Biodegradable Polymers for Bioapplications, Amercian Chemical Society, 1994.
Swelling Pressure of Poly (Glyceryl Methacrylate) Hydrogels, M. Refojo, pp. 697-704, 1972.

LandOfFree

Say what you really think

Search LandOfFree.com for the USA inventors and patents. Rate them and share your experience with other people.

Rating

Wear resistant hydrogel for bearing applications does not yet have a rating. At this time, there are no reviews or comments for this patent.

If you have personal experience with Wear resistant hydrogel for bearing applications, we encourage you to share that experience with our LandOfFree.com community. Your opinion is very important and Wear resistant hydrogel for bearing applications will most certainly appreciate the feedback.

Rate now

     

Profile ID: LFUS-PAI-O-3866005

  Search
All data on this website is collected from public sources. Our data reflects the most accurate information available at the time of publication.