Waveguide immunosensor with coating chemistry and providing...

Details Waveguide immunosensor with coating chemistry and providing... Waveguide immunosensor with coating chemistry and providing...

2006-04-04

2006-04-04

Chin, Christopher L. (Department: 1641)

Chemistry: molecular biology and microbiology

Apparatus

Including measuring or testing

C356S317000, C356S318000, C356S244000, C356S246000, C385S012000, C385S129000, C385S130000, C422S051000, C422S051000, C422S082050, C422S082080, C422S082110, C435S007500, C435S287200, C435S288700, C435S808000, C436S164000, C436S172000, C436S518000, C436S527000, C436S805000

Reexamination Certificate

active

07022515

ABSTRACT:
Methods and apparatus for evanescent light fluoroimmunoassays are disclosed. The apparatus employs a planar waveguide and optionally has multi-well features and improved evanescent field intensity. The preferred biosensor and assay method have the capture molecules immobilized to the waveguide surface by site-specific coupling chemistry. Additionally, the coatings used to immobilize the capture molecules provide reduced non-specific protein adsorption.

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