Radiant energy – Luminophor irradiation
Patent
1990-11-09
1991-10-29
Fields, Carolyn E.
Radiant energy
Luminophor irradiation
2504612, 136527, 385 30, 385 12, G01N 2164
Patent
active
050618571
ABSTRACT:
An optical waveguide-binding sensor which increases sensor sensitivity to fluorescence detection during assays of liquids based on adjustments in the V number along the optical waveguide. The sensing waveguide includes a mode converting section where the V number of the wavguide gradually increases from the distal sensing end of the mode converting section to the proximal end of the mode converting section. The gradually change in V number can be accomplished by either gradually inwardly tapering waveguide along the sensor portion from the proximal end, or by gradually varying the dopant concentration along the sensing portion. The sensor tapers in diameter to change the V number along the distal end of the optical waveguide. The present invention increases the efficiency of fluorescence detection by converting weakly-guided high-order modes of fluorescence radiation at the distal end into lower-order modes at the proximal and increases the efficiency of fluorescent excitation by converting low order mode entering the proximal end into weakly-guided high order modes at the sensing end. At the sensing end, these weakly guided modes cn strengthen the evanescent excitation wave.
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Thompson Richard B.
Villarruel Carl A.
Dunn Drew A.
Edelberg Barry A.
Fields Carolyn E.
McDonnell Thomas E.
The United States of America as represented by the Secretary of
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