Water soluble tri-substituted 1,2-dioxetane compounds and assay

Details Water soluble tri-substituted 1,2-dioxetane compounds and assay Water soluble tri-substituted 1,2-dioxetane compounds and assay

1997-07-17

1999-02-02

Owens, Amelia

Compositions

Chemiluminescent

C09K 300

Patent

active

058660453

ABSTRACT:
Stable, enzymatically triggered chemiluminescent 1,2-dioxetanes with improved water solubility and storage stability are provided. Dioxetanes further substituted with two or more water-solubilizing groups disposed on the dioxetane structure and an additional fluorine atom or lower alkyl group provide superior performance by eliminating the problem of reagent carryover when used in assays performed on capsule chemistry analytical systems. These dioxetanes display substantially improved stability on storage. Compositions comprising these dioxetanes, a non-polymeric cationic surfactant enhancer and optionally a fluorescer, for providing enhanced chemiluminescence are also provided.

REFERENCES:
patent: 5451347 (1995-09-01), Akhavan-Tafti
patent: 5484556 (1996-01-01), Akhavan-Tafti
patent: 5631167 (1997-05-01), Adolfsen et al.
patent: 5650099 (1997-07-01), Akhavan-Tifti

Affiliated with

Also associated with

Rating

Water soluble tri-substituted 1,2-dioxetane compounds and assay does not yet have a rating. At this time, there are no reviews or comments for this patent.

If you have personal experience with Water soluble tri-substituted 1,2-dioxetane compounds and assay , we encourage you to share that experience with our LandOfFree.com community. Your opinion is very important and Water soluble tri-substituted 1,2-dioxetane compounds and assay will most certainly appreciate the feedback.

Rate now

Comments { 0 }

Profile ID: LFUS-PAI-O-1114115