Drug – bio-affecting and body treating compositions – Designated organic active ingredient containing – Heavy metal containing doai
Patent
1999-03-05
1999-12-14
Shah, Mukund J.
Drug, bio-affecting and body treating compositions
Designated organic active ingredient containing
Heavy metal containing doai
556137, 546 5, 546 6, 548104, 548105, 548402, 548403, A61K 3128, C07F 1500
Patent
active
060018720
ABSTRACT:
The present invention relates to the treatment of tumors with a novel water soluble trans-platinum coordination compound having the general structural formula [PtBX.sub.m (NR*.sub.3)] where B is a planar, heterocyclic ring containing at least one nitrogen atom, and a pendant chelating group; and X is an anionic ligand; and R* is hydrogen or a lower alkyl.
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Sigel, Astrid and Sigel, Helmut, Metal Ions in Biological Systems, 1996, vol. 32, pp. 603-639.
Bierbach Ulrich
Farrell Nicholas P.
Shah Mukund J.
Sripada Pavanaram K
Virginia Commonwealth University
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