Water soluble thymidine derivative

Compositions – Solids with solution or dispersion aids

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Details

424 1, 424180, 424251, B01F 318, A01N 3114, A61K 3170, A61K 31505

Patent

active

043681387

ABSTRACT:
Thymidine may have its solubility in water increased by as much as 10 times or even more by combining the thymidine with a solubilizing agent, such as a salicylate derivative selected from salicylic acid, amino and methyleneamino substituted salicylic acids and salts and esters thereof. The thymidine and solubilizing agent may be combined by grinding in the dry state. The compounds are most conveniently used in approximately equimolar quantities.

REFERENCES:
patent: 2441341 (1948-05-01), Vitalis
patent: 2949449 (1960-08-01), Hoffer
patent: 3320236 (1967-05-01), Collins et al.
patent: 3579453 (1971-05-01), Dupre et al.

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