Water-soluble salts of tienilic acid

Details Water-soluble salts of tienilic acid Water-soluble salts of tienilic acid

1978-07-28

1980-12-16

Trousof, Natalie

Drug, bio-affecting and body treating compositions

Antigen, epitope, or other immunospecific immunoeffector

Allergen or component thereof

424316, 549 70, A61K 3138, C07D33328

Patent

active

042397715

ABSTRACT:
The invention provides water-soluble salts of tienilic acid, 2,3-dichloro-4-(2-thienylcarbonyl)-phenoxyacetic acid, and amino acids of the formula ##STR1## in which n is an integer of 1 to 5 and R represents a basic nitrogenous group, preferably an amino group or guanidino group. These salts, unlike the parent acid are water-soluble and are of good biodisponibility and may be used in injectable form, e.g. for emergency treatment.

REFERENCES:
patent: 2275809 (1942-03-01), Roberts
patent: 3758506 (1973-09-01), Godfroid et al.
patent: 3958004 (1976-05-01), Cragoe, Jr. et al.
patent: 3969529 (1976-07-01), Godfried et al.
patent: 4001301 (1977-01-01), Fried et al.
patent: 4017632 (1977-04-01), Thuillier et al.
Kirk-Othmer, "Encyclopedia of Chemical Technology", 2nd Ed., vol. 2, pp. 168-169.

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