Water-soluble rhodamine dyes conjugates

Chemistry: analytical and immunological testing – Fluorescent dyes

Reexamination Certificate

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Details

C435S006120, C435S007100, C435S007200, C536S004100, C536S023100, C536S024300, C536S025300, C536S026600, C530S300000, C530S350000

Reexamination Certificate

active

08030096

ABSTRACT:
The present invention provides novel, water-soluble, red-emitting fluorescent rhodamine dyes and red-emitting fluorescent energy-transfer dye pairs, as well as labeled conjugates comprising the same and methods for their use. The dyes, energy-transfer dye pairs and labeled conjugates are useful in a variety of aqueous-based applications, particularly in assays involving staining of cells, protein binding, and/or analysis of nucleic acids, such as hybridization assays and nucleic acid sequencing.

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