Chemistry: molecular biology and microbiology – Enzyme – proenzyme; compositions thereof; process for... – Stablizing an enzyme by forming a mixture – an adduct or a...
Patent
1991-04-04
1996-01-02
Russel, Jeffrey E.
Chemistry: molecular biology and microbiology
Enzyme , proenzyme; compositions thereof; process for...
Stablizing an enzyme by forming a mixture, an adduct or a...
436 86, 530405, 530406, 530409, 530410, 530411, C07K 1113, C12N 996
Patent
active
054807905
ABSTRACT:
A water-soluble protein conjugate modified by saccharides is covalently bound to a carbohydrate backbone via a saccharide group. Such protein conjugates modified by saccharides can be produced in a simple way by polymerizing a vinylsaccharide and conjugating in a known way the poly(vinylsaccharide) obtained in this way with the protein, which is preferably an enzyme. The protein conjugates according to the present invention are stable over long time periods at a high enzymatic activity and also in aqueous solution and are thus particularly suitable for use in test kits.
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Engelke Stephan
Klein Joachim
Muller Rolf-Joachim
Tischer Wilhelm
Boehringer Mannheim GmbH
Gesellschaft fur Biotechnologische Forschung mbH
Russel Jeffrey E.
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