Water soluble polymers having antifungal properties

Details Water soluble polymers having antifungal properties Water soluble polymers having antifungal properties

1992-03-19

1993-05-11

Page, Thurman K.

Drug, bio-affecting and body treating compositions

Effervescent or pressurized fluid containing

Organic pressurized fluid

424 47, 424 7814, 424 7872, 424 7825, 424409, 424DIG5, A61K 912, A61K 31785

Patent

active

052099229

ABSTRACT:
This invention relates to an antifungal block copolymer of poly(vinyl lactam) having the formula ##STR1## where m has a value of from 1 to 3 and from about 15 to about 25 wt. % of a quaternized amino alkyl acrylamide comonomer wherein the quaternizing anion is in part halide --O--CO(CH.sub.2).sub.s CH.dbd.CHZ wherein s has a value of from 4 to 14 and Z is hydrogen or a C.sub.1 to C.sub.4 alkyl radical, which copolymer is comprised of the following units ##STR2## wherein m has a value of from 1 to 3; p has a value of from 1 to 5; r has a value of from 2 to 6; each of X and Y is hydrogen or a C.sub.1 to C.sub.4 alkyl and each of R.sub.1, R.sub.2 and R.sub.3 is C.sub.1 to C.sub.4 alkyl. The invention also relates to the use of the above polymers as antifungal agents.

REFERENCES:
patent: 2776924 (1957-01-01), Martin
patent: 4329336 (1982-05-01), Su et al.
patent: 4513008 (1985-04-01), Revici et al.
patent: 4520132 (1985-05-01), Kinsolving
patent: 4704436 (1987-11-01), Barabas
patent: 4978525 (1990-12-01), Ohyama et al.

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