Water-soluble phenylpyridazine compounds and compositions...

Details Water-soluble phenylpyridazine compounds and compositions... Water-soluble phenylpyridazine compounds and compositions...

2005-03-01

2005-03-01

Bernhardt, Emily (Department: 1624)

Drug, bio-affecting and body treating compositions

Designated organic active ingredient containing

Heterocyclic carbon compounds containing a hetero ring...

C514S236500, C514S252020, C514S252030, C544S114000, C544S238000, C544S239000

Reexamination Certificate

active

06861428

ABSTRACT:
Compounds having the formula (1):wherein R1represents an alkyl or alkenyl group, R2and R3each independently represents a hydrogen atom or an alkyl, hydroxyalkyl, dihydroxyalkyl or alkynyl group, or R2and R3may be fused together with the adjacent nitrogen atom to form a substituted or unsubstituted, nitrogen-containing, saturated heterocyclic group, X, Y and Z each independently represents a hydrogen atom, an alkyl group, a halogen atom or the like, and n stands for an integer of from 1 to 5; and also to pharmaceutical compositions containing them. These compounds have inhibitory activity against IL-1β production, high water solubility and good oral absorbability.

REFERENCES:
patent: 4404203 (1983-09-01), Sircar
patent: 6403586 (2002-06-01), Ohkuchi et al.
patent: 20030225081 (2003-12-01), Nagato et al.
Livingston, Journal of Cellular Biochemistry, vol. 64, p. 19-26 (1997).

Affiliated with

Also associated with

Rating

Water-soluble phenylpyridazine compounds and compositions... does not yet have a rating. At this time, there are no reviews or comments for this patent.

If you have personal experience with Water-soluble phenylpyridazine compounds and compositions..., we encourage you to share that experience with our LandOfFree.com community. Your opinion is very important and Water-soluble phenylpyridazine compounds and compositions... will most certainly appreciate the feedback.

Rate now

Comments { 0 }

Profile ID: LFUS-PAI-O-3445372