Water-soluble lysine salts of (T)2-(4-Fluorophenyl)-alpha-methyl

Details Water-soluble lysine salts of (T)2-(4-Fluorophenyl)-alpha-methyl Water-soluble lysine salts of (T)2-(4-Fluorophenyl)-alpha-methyl

1989-01-05

1990-01-30

Daus, Donald D.

Drug, bio-affecting and body treating compositions

Designated organic active ingredient containing

Having -c-, wherein x is chalcogen, bonded directly to...

548217, C07D26356, A61K 3142

Patent

active

048974080

ABSTRACT:
Water-soluble salts of (+)2-(4-fluorophenyl)-alpha-methyl-5-benzoxazole acetic acid with DL-lysine, D-lysine or L-lysine, suitable for the preparation of medicinal specialities such as syrups, creams, suppositories, aqueous solutions for personal hygiene etc, and their preparation process.
Said salts are obtained by suspending said acid in an organic solvent soluble or partly soluble in water, adding an equivalent quantity of said lysine and crystallizing the salt obtained.

REFERENCES:
patent: 3912748 (1975-10-01), Evans
patent: 3988466 (1976-10-01), Takagi et al.
patent: 4434163 (1984-02-01), Lombardino
patent: 4652654 (1987-03-01), Verga et al.
patent: 4749694 (1988-07-01), Fix et al.
Chem. Abstr., vol. 82, Entry 118774 b, 1975.

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