Water-soluble lipophilic contrast agents

Drug – bio-affecting and body treating compositions – In vivo diagnosis or in vivo testing – Magnetic imaging agent

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424 9365, 556 50, 556 55, 556 63, 556 77, 556105, 556116, 556134, 556148, 534 16, 560169, 514492, 514502, 514558, 514563, 514836, A61B 5055

Patent

active

058041648

ABSTRACT:
The present invention relates to water-soluble, lipophilic contrast-enhancing agents, pharmaceutical compositions thereof and methods for diagnostic analysis, particularly NMR or MRI analysis using these contrast-enhancing agents. The water-soluble, lipophilic contrast-enhancing agents are chelates of a paramagnetic, ferromagnetic or diamagnetic metal ion(s) complexed with completing acids which contain at least one short-chain fatty acyl moiety having from about 0 to about 6 carbon atoms in its structure.

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