Water soluble hydrazones of 3-formylrifamycin SV, antibacterial

Drug – bio-affecting and body treating compositions – Antigen – epitope – or other immunospecific immunoeffector – Recombinant or stably-transformed bacterium encoding one or...

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2602393P, 542403, C07D49106, A61K 31395

Patent

active

042711550

ABSTRACT:
The invention relates to new water soluble 3-formylrifamycin SV hydrazones wherein the hydrazone moiety contains a phosphonoxy lower alkyl radical which imparts water solubility. The compositions containing said rifamycin derivatives are also an object of this invention. The new rifamycin derivatives and their pharmaceutical compositions are particularly suitable for parenteral administration.

REFERENCES:
patent: 3862934 (1975-01-01), Cricchio et al.
patent: 3865812 (1975-02-01), Cricchio et al.
patent: 4002752 (1975-01-01), Cricchio et al.
patent: 4002754 (1975-01-01), Cricchio et al.
patent: 4005076 (1977-01-01), Cricchio et al.
patent: 4193920 (1980-03-01), Konstantinova et al.

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