Water soluble high molecular weight polymerized drug preparation

Chemistry: natural resins or derivatives; peptides or proteins; – Peptides of 3 to 100 amino acid residues – Peptides containing saccharide radicals – e.g. – bleomycins – etc.

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424 7808, 424 7818, 536 64, 544235, 548422, 562571, C07K 900

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active

056937512

ABSTRACT:
This invention is a water-soluble high molecular polymerized drug comprising a water-soluble clock copolymer having a hydrophilic segment and a hydrophobic pharmacological-functioning segment to side chain of which a drug is bonded.
The hydrophilic first segments of the present invention include polyethylene glycol, polysaccharides, polyacrylamide, and so on.
The hydrophobic segments being attached to a drug include polyaspartic acid, polyglutamic acid, polylysine, or derivatives thereof.
Drugs to be attached to the hydrophobic segment include anti-cancer drugs, drugs for central nerve, drugs for circulatory organs, and so on.

REFERENCES:
patent: 4609546 (1986-09-01), Hiratani
patent: 4701521 (1987-10-01), Ryser et al.
patent: 4780421 (1988-10-01), Kameda et al.
patent: 4988625 (1991-01-01), Marburg et al.
patent: 5219564 (1993-06-01), Zalipsky
patent: 5412072 (1995-05-01), Sakurai et al.
D. Deprez-De Campeneere et al., Cancer Chemother. Pharmacol. 2:25-30 (1979).
Yokoyama et al., 1987, Die Makromoleculare Chemie: Rapid Comm. 8:431-35.
Yokoyama et al., 1989, Die Makromoleculare Chemie Macromolecular Chemistry & Physc. 190:2041-54.
Yokoyama et al., 1990, J. Controlled Release, 11:269-78.

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