Water soluble fluorescent compounds

Details Water soluble fluorescent compounds Water soluble fluorescent compounds

2011-01-11

2011-01-11

Staples, Mark (Department: 1637)

Organic compounds -- part of the class 532-570 series

Organic compounds

Carbohydrates or derivatives

C530S300000, C530S802000, C548S455000, C435S006120

Reexamination Certificate

active

07868157

ABSTRACT:
The invention provides a novel class of fluorescent compounds. Also provided are conjugates of the fluorescent compounds, methods of using the fluorescent compounds and their conjugates as well as kits including the fluorescent compounds and their conjugates.

REFERENCES:
patent: 3493639 (1970-02-01), Tavs
patent: 4150021 (1979-04-01), Swidler et al.
patent: 5268486 (1993-12-01), Waggoner et al.
patent: 5486616 (1996-01-01), Waggoner et al.
patent: 5877310 (1999-03-01), Reddington et al.
patent: 6348599 (2002-02-01), Cummins et al.
patent: 6706879 (2004-03-01), Anderson et al.
patent: 2005/0272088 (2005-12-01), Cook et al.
patent: 2006/0035262 (2006-02-01), Cook et al.
Gale, et al., “The Amidomethylation and Bromination of Fischer's Base. The Preparation of Some New Polymethine Dyes,”Australian J. Chem, 1977, 30:689-694.
Devlin, et al., “Homogeneous Detection of Nucleic Acids by Transient-State Polarized Fluorescence,”Clin. Chemistry, 1993, 39(9):1939-1943.
Spatola, A.F.,Chemistry and Biochemistry of Amino Acids, Peptides and Proteins, B. Weinstein, eds., Marcel Dekker, New York, vol. 7, p. 267-357 (1983).
Still, et al., “Rapid Chromatographic Technique for Preparative Separations with Moderate Resolution,”J. Org. Chem., 1978, 43(14):2923-2925.
Southwick, et al., “Cyanine Dye Labeling Reagents—Carboxymethylindocyanine Succinimidyl Esters,”Cytometry, 1990, 11:418-430.
Borbas, K.E., et al., “Bioconjugatable Porphyrins bearing a Compact Swallowtail Motif for Water Solubility ”Bioconjugate Chemistry, 17:638-653 (2006).
Gale, et al., “The Amidomethylation and Bromination of Fischer's Base. The Preparation of Some New Polymethine Dyes,”Aust. J. Chem., 1977, 30:689-694.
Goussu, C., et al., “Optimized Synthesis of Functionalized Fluorescent Oligodeoxynucleotides for Protein Labeling”Bioconjugate Chemistry, 16:465-470 (2005).
Law, et al., “Squaraine chemistry. On the anomalous mass spectra of bis(4-dimethylaminophenyl)squaraine and its derivatives”Can. J. Chem., 64:1607-1619 (1986).
Mujumdar, R.B., et al., “Cyanine Dye Labeling Reagents: Sulfoindocyanine Succinimidyl Esters”Bioconjugate Chem., 4(2):105-111 (Mar./Apr. 1993).
Mujumdar, S.R., et al., “Cyanine Dye Labeling Reagents: Sulfobenzindocyanine Succinimidyl Esters”Bioconjugate Chem., 7:356-362 (1996).
Narayanan, N., et al., “A New Method for the Synthesis of Heptamethine Cyanine Dyes: Synthesis of Near-Infra Red Labels”J. Org. Chem., 60:2391-2395 (1995).
Oswald, B., et al., “Synthesis, Spectral Properties, and Detection Limits of Reactive Squaraine Dyes, a New Class of Diode Laser Compatible Fluorescent Protein Labels”Bioconj. Chem., 10:925-931 (1999).
Oswald, B., et al., “Novel Diode Laser-compatible Fluorophores and Their Application to Single Molecule Detection, Protein Labeling and Fluorescence Resonance Energy Transfer Immunoassay”Photochemistry and Photobiology, 74(2):237-245 (2001).
Reddington, M.V., “New Glycoconjugated Cyanine Dyes as Fluorescent Labeling Reagents”J. Chem. Soc. Perkin Trans., 1:143-147 (1998).
Reynolds, G.A., et al., “Stable Heptmethine pyrilium Dyes That Absorb in the Infrared”J. Org. Chem., 42(5):885-888 (1977).
Sharman, W.M., et al., “Novel Water Soluble Phthalocyanines with Phosphonate Moieties on the Benzo Rings”Tetrahedron Letters37(33):5831-5834 (1996).
Tavs, P.,Chem. Ber., “Reaction of Aryl Halides with Trialkyl Phosphites and Dialkyl Benzenephosphonites to Aromatic Phosphonates and Phosphinates by Nickel Salt Catalysed Arylation,” 103:2428-2436 (1970).

Affiliated with

Also associated with

Rating

Water soluble fluorescent compounds does not yet have a rating. At this time, there are no reviews or comments for this patent.

If you have personal experience with Water soluble fluorescent compounds, we encourage you to share that experience with our LandOfFree.com community. Your opinion is very important and Water soluble fluorescent compounds will most certainly appreciate the feedback.

Rate now

Comments { 0 }

Profile ID: LFUS-PAI-O-2627773