Water-soluble derivatives of 6,6'-methylene-bis-(2,2,4-trimethyl

Details Water-soluble derivatives of 6,6'-methylene-bis-(2,2,4-trimethyl Water-soluble derivatives of 6,6'-methylene-bis-(2,2,4-trimethyl

1980-07-02

1982-10-26

Springer, David B.

Organic compounds -- part of the class 532-570 series

Organic compounds

Heterocyclic carbon compounds containing a hetero ring...

424258, C07D21512

Patent

active

043563066

ABSTRACT:
The invention relates to water-soluble alkali salts of mono- and disulfonic acid derivatives and mono- and disulfonamide derivatives of 6,6'-methylene-bis-(2,2,4-trimethyl-1,2-dihydroquinoline) and dimer and/or trimer condensation products thereof bound with a methylene bridge at the 8 or 8' position. The new compounds are radioprotective and radiosensibilizers at the same time, and may be used both in the therapy and prophylaxis of malignant tumors.

REFERENCES:
patent: 3047521 (1962-07-01), Harman
patent: 4025631 (1977-05-01), Bar et al.

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