Water-soluble concentrates containing cyclosporins

Details Water-soluble concentrates containing cyclosporins Water-soluble concentrates containing cyclosporins

1996-09-17

1998-08-25

Gerstl, Robert

Drug, bio-affecting and body treating compositions

Designated organic active ingredient containing

Peptide containing doai

A61K 3800

Patent

active

057983330

ABSTRACT:
The invention is directed to pharmaceutical compositions which enable high concentrations of a cyclosporin and are water-soluble, such that the compositions will dissolve in aqueous media without precipitation of the cyclosporin. The compositions comprise a cyclosporin dissolved in tocophersolan and a hydrophillic organic solvent, preferably propylene glycol.

REFERENCES:
patent: 4388307 (1983-06-01), Sandoz
patent: 5342625 (1994-08-01), Sandoz
patent: 5583105 (1996-12-01), Kovacs

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