Drug – bio-affecting and body treating compositions – Designated organic active ingredient containing – Peptide containing doai
Patent
1992-07-06
1995-05-16
Schain, Howard E.
Drug, bio-affecting and body treating compositions
Designated organic active ingredient containing
Peptide containing doai
514 12, 514964, A61K 3814
Patent
active
054160715
ABSTRACT:
(1) A composition which comprises erythropoietin and hyaluronic acid shows a sustained-release of the medicine in a living body, and
(2) A water-soluble composition which comprises (a) a pharmacologically active polypeptide secreted by an animal body or its derivative or a chemically synthesized pharmacologically active substance, (b) a water-soluble species of hyaluronic acid or its nontoxic salt and (c) a water-soluble protein injectable into body fluids without showing any substantial pharmacological activity brings about a prolonged action in vivo of a pharmacologically active substance. In addition, the composition can be administered using a small-gauge needle and thereby contributes ot relieving pain in patients.
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Igari Yasutaka
Ogawa Yasuaki
Yamada Minoru
Conlin David G.
Lowen Cara Z.
Neuner George W.
Schain Howard E.
Takeda Chemical Industries Ltd.
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