Water-soluble chitosan having low endotoxin concentration...

Organic compounds -- part of the class 532-570 series – Organic compounds – Carbohydrates or derivatives

Reexamination Certificate

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C536S055300

Reexamination Certificate

active

07125967

ABSTRACT:
Water-soluble chitosan having a low concentration of endotoxin is disclosed. Products containing the water-soluble chitosan are also disclosed. Methods of making and using water-soluble chitosan having a low concentration of endotoxin are further disclosed.

REFERENCES:
patent: 4168112 (1979-09-01), Ellis et al.
patent: 4259202 (1981-03-01), Tanaka et al.
patent: 4826826 (1989-05-01), Conti
patent: 4885168 (1989-12-01), Hashimoto et al.
patent: 4909942 (1990-03-01), Sato et al.
patent: 4979959 (1990-12-01), Guire
patent: 4996307 (1991-02-01), Itoi et al.
patent: 5057542 (1991-10-01), Leuba et al.
patent: 5169535 (1992-12-01), Adachi et al.
patent: 5290813 (1994-03-01), Clark et al.
patent: 5409731 (1995-04-01), Nakagawa et al.
patent: 5422116 (1995-06-01), Yen et al.
patent: 5451237 (1995-09-01), Vehige
patent: 5520920 (1996-05-01), Castillo et al.
patent: 5536155 (1996-07-01), Futaki et al.
patent: 5549919 (1996-08-01), Ueno et al.
patent: 5589591 (1996-12-01), Lewis
patent: 5658915 (1997-08-01), Abe et al.
patent: 5891913 (1999-04-01), Sallmann et al.
patent: 6284749 (2001-09-01), Castillo et al.
patent: 6451772 (2002-09-01), Bousman et al.
patent: 6589999 (2003-07-01), Gurny et al.
patent: 2002/0018732 (2002-02-01), Hung et al.
patent: 1229071 (1999-09-01), None
patent: 362184002 (1987-08-01), None
patent: 63169975 (1988-08-01), None
patent: 1010970 (1989-01-01), None
patent: 1050014 (1989-02-01), None
patent: 1293314 (1989-11-01), None
patent: 3102313 (1991-04-01), None
patent: 5142502 (1993-06-01), None
patent: 6181970 (1994-07-01), None
patent: 7223966 (1995-08-01), None
patent: 7324014 (1995-12-01), None
patent: WO 94/13774 (1994-06-01), None
patent: WO 96/20730 (1996-07-01), None
patent: WO 97/06782 (1997-02-01), None
patent: WO 99/40790 (1999-08-01), None
patent: WO 00/30609 (2000-06-01), None
patent: WO 02/09513 (2002-02-01), None
U.S. Appl. No. 07/986,959, Powell et al., “Compositions and Methods for Inhibiting and Reducing Lysozyme Deposition on Hydrophilic Contact Lenses.” 27 pgs. (filed Dec. 9, 1992).
Brochure, “Limulus Amebocyte Lysate Endosafe KTA™, U.S. License No. 1197, Multi-Test Vial For Endotoxin (Pyrogen) Detection,”Charles River Endosafe, 2 pgs., (Date Unknown).
Brochure, “Amino acid based surfactant, Amisoft,”Munomoto, 6 pgs. (Date Unknown).
Brochure, “HAMPOSYL N-Acyl Sarcosinate Surfactants,”Hampshire, A Subsidiary of The Dow Chemical Company, 30 pgs. (Date Unknown).
Bough, W. et al., “Influence of Manufacturing Variables on the Characteristics and Effectiveness of Chitosan Products. II. Coagulation of Activated Sludge Suspensions,”Biotechnology and Bioengineering. vol. XX, No. 12, pp. 1945-1955 (Dec. 1978).
Davydova, V. et al., “Interaction of Bacterial Endotoxins with Chitosan. Effect of Endotoxin Structure, Chitosan Molecular Mass, and Ionic Strength of the Solution on the Formation of the Complex,”Biochemistry, vol. 65, No. 9, pp. 1082-1090 (2000).
Felt, O. et al., “Topical use of chitosan in ophthalmology: tolerance assessment and evaluation of precorneal retention,”International Journal of Pharmaceutics, vol. 180, pp. 185-193 (1999).
Felt, O. et al, “Chitosan as Tear Substitute: A Wetting Agent Endowed with Antimicrobial Efficacy,”Journal of Ocular Pharmacology And Therapeutics, vol. 16, No. 3, pp. 261-270 (2000).
Felt, O. et al., “Delivery of Antibiotics to the Eye Using a Positively Charged Polysaccharide as Vehicle,”AAPS Pharmaceutical, http://www.pharmsci.org/scientificjournals/pharmsci/journal/01—34.html, Article 34, 9 pgs. (2001).
Hirano, S. et al., “Selective N-acylation of chitosan*,”Carbohydrate Research, vol. 47, pp. 315-320 (1976).
Kristiansen, A. et al., “The interactions between highly de-N-acetylated chitosans and lysozyme from chicken egg white studied by1H-NMR spectroscopy,”Eur. J. Biochem., vol. 251, pp. 335-342 (1997).
Kristiansen, A. et al., “Competitive binding of highly de-N-acetylated chitosans and N,N′-diacetylchitobiose to lysozyme from chicken egg white studied by1H NMRspectroscopy,”Carbohydrate Research, vol. 289, pp. 143-150 (1996).
Kurita, K. et al., “Studies on Chitin, 3*). Preparation of Pure Chitin, Poly(N-acetyl-D-glucosamine), from the Water-Soluble Chitin,”Makromol. Chem., vol. 178, pp. 2595-2602 (1977).
Kurita, K. et al., “Solubilization of a Rigid Polysaccharide: Controlled Partial N-Acetylation of Chitosan to Develop Solubility,”Carbohydrate Polymers, vol. 16, pp. 83-92 (1991).
LeHoux, J. et al., “Some Effects of Chitosan on Liver Function in the Rat*,”Endocrinology, vol. 132, No. 3, pp. 1078-1084 (1993).
Sannan, T. et al., “Studies on Chitin, 2*), Effect of Deacetylation on Solubility,”Makromol. Chem.,vol. 177, pp. 3589-3600 (1976).
Wu, A. et al., “Influence of Manufacturing Variables on the Characteristics and Effectiveness of Chitosan Products. III. Coagulation of Cheese Whey Solids,”Biotechnology and Bioengineering, vol. XX, No. 12, pp. 1957-1966 (Dec. 1978).

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