Water soluble carrier-bound penicillinacylase

Details Water soluble carrier-bound penicillinacylase Water soluble carrier-bound penicillinacylase

1975-10-30

1979-09-11

Naff, David M.

Chemistry: molecular biology and microbiology

Micro-organism, tissue cell culture or enzyme using process...

Preparing compound having a 1-thia-4-aza-bicyclo

435178, 435179, C12D 900, C12D 906, C07G 702

Patent

active

041674464

ABSTRACT:
A water-soluble non-colloidal penicillinacylase preparation containing penicillinacylase covalently bound to a water-soluble carrier is produced by reacting penicillinacylase with an activated derivative of a water soluble polysaccharide in aqueous solution. The water-soluble penicillinacylase preparation efficiently hydrolyzes penicillin and permits recovery of 6-aminopenicillanic acid efficiently in extremely high purity.

REFERENCES:
patent: 3639213 (1972-02-01), Ginger et al.
patent: 3649457 (1972-03-01), Westman
patent: 3715277 (1973-02-01), Dinella et al.
patent: 3736230 (1973-05-01), Delin et al.
patent: 3791927 (1974-02-01), Forgione et al.

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