Water soluble C-ring analogues of 20(S)-camptothecin

Details Water soluble C-ring analogues of 20(S)-camptothecin Water soluble C-ring analogues of 20(S)-camptothecin

1996-12-19

1999-10-26

Rotman, Alan L.

Drug, bio-affecting and body treating compositions

Designated organic active ingredient containing

Having -c-, wherein x is chalcogen, bonded directly to...

546 48, A61K 3147, C07D491147

Patent

active

059729554

ABSTRACT:
Novel water soluble C-ring analogs of 20(S)-camptothecin having the formula 1. ##STR1## The compounds of the formula 1 are prepared from the compounds of the formula 12 having C-20(S) chiral carbon. The compounds of the formula 1 possess potent anti-cancer and anti-viral properties.

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