Drug – bio-affecting and body treating compositions – Antigen – epitope – or other immunospecific immunoeffector – Bacterium or component thereof or substance produced by said...
Patent
1982-04-13
1984-02-28
Ford, John M.
Drug, bio-affecting and body treating compositions
Antigen, epitope, or other immunospecific immunoeffector
Bacterium or component thereof or substance produced by said...
544 49, C07D40112, A61K 3154
Patent
active
044341636
ABSTRACT:
The water-soluble lysine and arginine salts of N-(2-pyridyl)-2-methyl-4-hydroxy-2H-1,2-benzothiazine-3-carboxamide 1,1-dioxide have been prepared. These novel salts are useful in therapy as non-steroidal anti-arthritic agents, especially when administered by the parenteral route. Methods for preparing these salts from the corresponding acidic starting material and the appropriate amine base are provided.
REFERENCES:
patent: 3591584 (1971-07-01), Lombardino
patent: 4116964 (1978-09-01), Zinnes et al.
patent: 4233299 (1980-11-01), Trummlitz et al.
patent: 4289879 (1981-09-01), Lombardino
J. G. Lombardino et al., "Potent Antiinflammatory N-Heterocyclic 3-Carboxamides of 4-Hydroxy-2-methyl-2H-1,2-benzothiazine 1,1-Dioxide", Journal of Medicinal Chemistry, vol. 16, No. 5, p. 493, (1973).
E. Nelson, "Solution Rate of Theophylline Salts and Effects from Oral Administration", Journal of the American Pharmaceutical Association, vol. 46, No. 10, p. 607, (1957).
A. E. Vivino, "Blood Theophylline Concentration Following the Oral Administration of Theophylline Ethylenediamine and Theophylline Isopropanolamine", Journal of the American Pharmaceutical Association, vol. 43, p. 234, (1954).
Ford John M.
Knuth Charles J.
Pfizer Inc.
Richardson Peter C.
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