Water-soluble alkanoyloxy and alkoxycarbonyloxy rifampicin deriv

Details Water-soluble alkanoyloxy and alkoxycarbonyloxy rifampicin deriv Water-soluble alkanoyloxy and alkoxycarbonyloxy rifampicin deriv

1984-06-29

1986-04-29

Daus, Donald G.

Chemistry of carbon compounds

Miscellaneous organic carbon compounds

C-metal

514183, C07D49808

Patent

active

045855897

ABSTRACT:
The present invention is directed to new water soluble rifampicin derivatives which are suitable for preparing aqueous solutions for oral or parenteral administration. The new derivatives of the invention are 4 and/or 8 alkanoyl or alkanoyloxyalkyl esters of rifampicin and possess essentially the same antibacterial activity of this widely known antibiotic substance.

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Greenaway et al., Chem. Abst. 99-63902k (1983).
Tan et al., Chem. Abst. 102-84467t (1985).
Malabarba et al., Chem. Abst. 103-6153u (1985).

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