Water-soluble adduct of norfloxacin

Drug – bio-affecting and body treating compositions – Designated organic active ingredient containing – Having -c- – wherein x is chalcogen – bonded directly to...

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Details

544363, A61K 31495, C07D40114

Patent

active

047925523

ABSTRACT:
The present invention relates to an adduct of nicotinic acid with 1-ethyl-6-fluoro-1,4-dihydro-4-oxo-7-(1-piperazinyl)-3-quinolinecarboxylic acid (Norfloxacin) in particular in a ratio of 1:1. The invention relates also to pharmaceutical compositions and to aqeuous solutions comprising said adduct.

REFERENCES:
patent: 4146719 (1979-03-01), Irikura
patent: 4292317 (1981-09-01), Pesson
patent: 4352803 (1982-10-01), Matsumoto et al.
patent: 4522819 (1985-06-01), Fox et al.
patent: 4670440 (1987-06-01), Sz/u/ ts et al.

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