Water soluble 1,2-diaminocyclohexane platinum (IV) complexes as

Details Water soluble 1,2-diaminocyclohexane platinum (IV) complexes as Water soluble 1,2-diaminocyclohexane platinum (IV) complexes as

1988-11-22

1991-08-20

Prescott, Arthur C.

Organic compounds -- part of the class 532-570 series

Organic compounds

Heavy metal containing

C07F 1500, A61K 3128

Patent

active

050415786

ABSTRACT:
Water-soluble complexes having the formula: ##STR1## and stereoisomers thereof, where Z.sup.1 and Z.sup.2 are halogens and X is selected from the group consisting of sulfate, phosphate, nitrate, monocarboxylate, and dicarboxylate, have been found to have desirable antitumor activity, as well as relatively low levels of toxicity.

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