Water soluble 1,2-diaminocyclohexane platinum (IV) complexes as

Details Water soluble 1,2-diaminocyclohexane platinum (IV) complexes as Water soluble 1,2-diaminocyclohexane platinum (IV) complexes as

1992-08-07

1994-06-07

Prescott, Arthur C.

Drug, bio-affecting and body treating compositions

Designated organic active ingredient containing

Heterocyclic carbon compounds containing a hetero ring...

514188, 540465, 540541, 548402, 549 3, 549206, 549208, 546 11, 556137, C07F 1500, A61K 31555

Patent

active

053189620

ABSTRACT:
Water-soluble complexes having the formula: ##STR1## and stereoisomers thereof, where Z.sup.1 and Z.sup.2 are halogens, and X.sup.1 and X.sup.2 are selected from the group consisting of sulfate, phosphate, nitrate, and monocarboxylate, or are jointly dicarboxylate, have been found to have desirable antitumor activity, as well as relatively low levels of toxicity.

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