Drug – bio-affecting and body treating compositions – Solid synthetic organic polymer as designated organic active... – Ion exchange resin
Patent
1997-12-29
2000-10-10
Page, Thurman K.
Drug, bio-affecting and body treating compositions
Solid synthetic organic polymer as designated organic active...
Ion exchange resin
424 7827, 526290, 528392, A61K 31785
Patent
active
061299103
ABSTRACT:
The present invention relates to a method for sequestering bile acids in a patient and to particular polymers for use in the method. The method comprises the step of orally administering to a mammal, such as a human, a therapeutically effective amount of a new class of water-insoluble noncrosslinked amine polymers.
The water-insoluble noncrosslinked amine polymer comprises an amine-containing monomer or repeat unit which has one or more substituents bound to an amine nitrogen of the amine polymer. The substituent or substituents which are bound to the amine nitrogens of the amine polymer include a hydrophobic moiety and/or a quaternary amine-containing moiety.
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United States Ser. No. 08/777,408, filed on Dec. 30, 1996, "Poly (diallylamine)--Based Bile Acid Sequestrant" by Stephen Randall Holmes-Farley, Pradeep K. Dhal and John S. Petersen.
Holmes-Farley Stephen Randall
Mandeville, III W. Harry
Bawa R.
GelTex Pharmaceuticals Inc.
Page Thurman K.
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