Water-insoluble derivatives of hyaluronic acid and their methods

Details Water-insoluble derivatives of hyaluronic acid and their methods Water-insoluble derivatives of hyaluronic acid and their methods

1994-08-18

1996-03-26

Knode, Marian C.

Drug, bio-affecting and body treating compositions

Designated organic nonactive ingredient containing other...

Carbohydrate or lignin, or derivative

514 54, 424447, 424449, 424488, 424 103, A61K 4736, A61K 970, A01N 2510, A61L 1528

Patent

active

055020810

ABSTRACT:
This invention describes a method for preparing water-insoluble biocompatible gels, films and sponges by reacting hyaluronic acid, or a salt thereof, with a carbodiimide in the absence of a nucleophile or a polyanionic polysaccharide. The water-insoluble gels, films and sponges of this invention may be used as surgical aids to prevent adhesions of body tissues and as drug delivery vehicles.

REFERENCES:
patent: 4937270 (1990-06-01), Hamilton et al.
patent: 5017229 (1991-05-01), Burns et al.
patent: 5128326 (1992-07-01), Balazs et al.

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