Water-insoluble biospecific absorbent containing argininal deriv

Catalyst – solid sorbent – or support therefor: product or process – Biospecific material – or produced by enzyme or microorganism

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210656, 2601125R, 435179, 435181, 435215, 502403, 502404, B01J 2026, C12N 972, A61K 3754, C07C10352

Patent

active

045254656

ABSTRACT:
A biospecific adsorbent comprising pyroglutamyl-lysyl-leucyl-argininal combined with a water-insoluble support is provided. This biospecific adsorbent is useful as an adsorbent for use in affinity chromatography and can be utilized for the purification of proteases such as urokinase.

REFERENCES:
patent: 4259447 (1981-03-01), Hafeli
patent: 4334972 (1982-06-01), Soderberg
patent: 4415665 (1983-11-01), Mosbach
Anal. Chem.--vol. 53--No. 3--Mar. 1981--pp. 489-495, "Liquid Chromatographic Separation of Amino Acids, Peptides and Derivatives on a Porous Polystyrene-Divinylbenzene Copolymer" by Z. Iskandarani and D. Pietrzyk.

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