Water-dispersible or water-soluble D-tocotrienol compounds and m

Organic compounds -- part of the class 532-570 series – Organic compounds – Heterocyclic carbon compounds containing a hetero ring...

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549412, C07D31172

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active

058697047

ABSTRACT:
The invention relates to a water-dispersible or water-soluble compound having the structure I ##STR1## wherein, R.sup.1,R.sup.2, and R.sup.3 are, independently, hydrogen or methyl, and R.sup.4 is--(CH.sub.2 CH.sub.2 O).sub.n CH.sub.2 CH.sub.2 OH, wherein n is from 10 to 100, wherein compound I is the substantially pure D-enantiomer. The invention further relates to a water-dispersible or water-soluble compound having the structure II ##STR2## wherein, R.sup.1, R.sup.2, and R.sup.3 are, independently, hydrogen or methyl, or the salt thereof, wherein compound II is the substantially pure D-enantiomer. The invention further relates to methods for making the tocotrienol compounds of the present invention.

REFERENCES:
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patent: 3102078 (1963-08-01), Robeson
patent: 5348974 (1994-09-01), Wright et al.
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patent: 5430021 (1995-07-01), Rudnic et al.
patent: 5554647 (1996-09-01), Perricone
patent: 5591772 (1997-01-01), Lane et al.
patent: 5670668 (1997-09-01), Hyatt
Goh et al., Tocotrienols from Palm Oil; Electron Spin Resonance Spectra of Tocotrienoxyl Radicals, J. Am. Oil Chem. Soc., 67(4), 250-4, 1990 (abstract).

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