Water channel

Drug – bio-affecting and body treating compositions – Preparations characterized by special physical form – Liposomes

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435 712, 4351723, 4352402, 4352523, 43525233, 43525411, 4353201, 435 691, 530350, A61K 9127, C12N 1500, C07K 100, C07K 104

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057859868

ABSTRACT:
A WCH-1 cDNA probe specific to mRNA expressing a water channel localized in the kidney collecting tubule and complementary to said mRNA, and the sequence has been identified. The same is obtained by

REFERENCES:
Winstow et al. "Tandem sequence repeats in transmembrane channel proteins", Treands Biochem. Sci. 16: 170-171, May 1991.
Nielson et al. "Cellular and subcellular immunolocalization of vasopressin-regulated water channel in rat kidney", Proc. Nat. Acad. Sci. USA 90:11663-11667, Dec. 1993.
Bear et al., "Purification and Functional Reconstitution of the Cystic Fibrosis Transmembrane Conductance Regulator (CFTR)", Cell 68:809-818 (1992).
Cohen et al., "Nonchromosal Antibiotic Resistance in Bacteria: Genetic Transformation of Escherica coli by R-Factor DNA", Proc. Natl. Acad. Sci. USA 69:2110-2114 (1972).
Dascal, "The Use of Xenopus Oocytes for the Study of Ion Channels", CRC Crit. Rev. Biochem. 22:317-387 (1987).
Denker et al., "Identification, Purification, and Partial Characterization of a Novel Mr 28,000 Integral Membrane Protein from Erythrocytes and Renal Tubules", J. Biol. Chem. 263:15634-15642 (1988).
Ganote et al., "Ultrastructural Studies of Vasopressin Effect on Isolated Perfused Renal Collecting Tubules of the Rabbit", J. Cell Biol. 36:355-367 (1968).
Handler, "Antidiuretic hormone moves membranes", Am. J. Physiol. 255:F375-F382 (1988).
Harris et al., "Current Understanding of the Cellular Biology and Molecular Structure of the Antidiuretic Hormone-stimulated Water Transport Pathway", J. Clin. Invest. 88:1-8 (1991).
Kagawa et al., "Partial Resolution of the Enzymes Catalyzing Oxidative Phosphorylation", J. Biol. Chem. 248:676-684 (1973).
Kasahara et al., "Reconstruction and Purification of the D-Glucose Transporter from Human Erythrocytes", J. Biol. Chem., 252:7384-7390 (1977).
Kent et al., "Nucleotide and derived amino-acid sequence of the major intrinsic protein of rat eye-lens", Nucl. Acid. Res. 18:4256 (1990).
Kennelly et al., "Consensus Sequences as Substrate Specificity Determinants for Protein Kinases and Protein Phosphatases", J. Biol. Chem. 266:15555-15558 (1991).
Kirk et al., "Water Transport and Osmoregulation by Antidiuretic Hormone in Terminal Nephron Segments", Kidney: Physiologh and Pathophysiology (eds Seldin, D. W. and Giebisch, G.) 1693-1725 Raven Press, New York (1992).
Knepper et al., "Urinary Concentration and Dilution" Kidney (eds Brenner, B. M. & Rector, F. C., Jr.) 445-482 W.B. Saunders, Philadelphia (1991).
Kornfeld et al., "Assembly of Asparagine-Linked Oligosaccharides", Ann. Rev. Biochem. 54:631-664 (1985).
Kozak, "An analysis of 5'-noncoding sequences from 699 vertebrate messenger RNAs", Ncl. Acid Res. 15:8125-8148 (1987).
Kuwahara et al., "Rapid Development of Vasopressin-Induced Hydroosmosis in Kidney Collecting Tubules Measured by a New Fluorescence Technique", Biophys. J. 54:595-602.
Kyte et al., "A Simple Method for Displaying the Hydropathic Character of a Protein", J. Mol. Bio. 157:105-132 (1982).
Mishina et al., "Expression of functional acetylcholine receptor from cloned cDNAs", Nature (London) 307:604-608 (1984).
Moriyama et al., "Detection of specific mRNAs in single nephron segments by use of the polymerase chain reaction", Am. J. Physiol. 258:F1470-F1474 (1990).
Newman et al., "Solubilation and Reconstitution of the Lactose Transport System from Eschericia coli", J. Biol. Chem., 255:10583-10586 (1980).
Orloff et al., Am. J. Med. 42:757-768 (1967).
Pao et al., "Evolution of the MIP family of integral membrane transport proteins", Mol. Microbiol. 5:33-37 (1991).
Pisano et al., "Genomic Cloning, Complete Nucleotide Sequence, and Structure of the Human Gene Encoding the Major Intrinsic Protein (MIP) of the Lens"Genomics 11:981-990 (1991).
Preston et al., "Appearance of Water Channels in Xenopus Oocytes Expessing Red Cell CHIP28 Protein", Science 256:385-387(1992).
Preston et al., "Isolation of the cDNA for erythrocyte integral membrane protein of 28 kilodaltons: Member of an ancient channel family", Proc. Natl. Acad. Sci. USA 8:11110-11114 (1991)
Showsky et al., J. Lab. Clin. Med. 80:134-144 (1972).
Sigel, "Use of Xenopus Oocytes for the Functional Expression of Plasma Membrane Proteins", J. Membrane Biol. 117:201-221 (1990).
Terada et al., "RT-PCR microlocalization of mRNA for guanylyl cyclase-coupled ANF receptor in rat kidney", Am. J. Physiol. 261:F1080-F1087 (1991).
Tonghui et al., "Cloning of a Novel Rat Kidney cDNA Homologous to CHIP28 and WCH-CD Water Channels" Biochemical and Biophysical Research Conmmunications 197:654-659 (1993).
Verkman, Annu. Rev. Physiol. 54:97-108 (1992).
Zeidel et al., "Reconstittution of Functional Water Channels in Liposomes Containing Purified Red Cell CHIP 28 Protein" Biochem. 31:7436-7440 (1992).
Zhang et al.,"Water and urea permeability properties of Xenopus oocytes: exression of mRNA from toad urinary bladder", Am. J. Physiol. 260:C26-C34 (1991).
Yamamoto, T. et al., "Vasopressin increases AQP-CD water channel in apical membranes of collecting duct red cells in Brattleboro rats,"The American Physiological Society (1995) Rapid Communication:C1546-1551.
Nielsen, S. "Vasopressin increases water permeability of kidney collecting duct by inducing translocation of aquaporin-CD water channels to plasma membrane, " Proc. Natl. Acad. Sci. USA (Feb. 1995). 92:1013-1017.
Deen, P.M.T. et al., "Requirement of Human Renal Water Channel Aquaporin-2 for Vasopressin-Dependent Concentration of Urine," Sciences (1 Apr. 1994) 264:92-95.
Echevarria M,. et al., "Expression of Multiple Water Channel Activities in Xenopus Oocytes Injected with mRNA from Rat Kidney,"The Journal of General Physiology (1993) 101:827-841.
Fushimi, K. et al., "Cloning and expression of apical membrane water channel of rat kidney collecting tubule," Nature (11 Feb., 1993) 361:549-552.

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