Drug – bio-affecting and body treating compositions – Antigen – epitope – or other immunospecific immunoeffector – Recombinant or stably-transformed bacterium encoding one or...
Patent
1975-07-30
1976-12-07
Turner, V. D.
Drug, bio-affecting and body treating compositions
Antigen, epitope, or other immunospecific immunoeffector
Recombinant or stably-transformed bacterium encoding one or...
424329, 424361, A01N 918
Patent
active
039963780
ABSTRACT:
Products and processes of a water-based formulation of methylene bis thiocyanate (MBT) in a xanthan gel, which is a hydrophilic colloid in water where the colloid is utilized at a concentration of about 0.02-2.0 weight percent and preferably 0.1-1.0 of the colloid carrier. In use in water treatment, this dosage is adjusted so that use dosage contains about 2-1000 ppm by weight of the microbicide and preferably 20-200 ppm. Alternatively, a ternary formulation may be used containing methylene bis thiocyanate plus an auxiliary fast-acting biocide in the same xanthan gel. The auxiliary microbicide is selected from an n-alkyl (C.sub.12 -C.sub.18) dimethyl(benzyl)ammonium chloride such as the preferred quaternary; i.e., tetradecyl benzyl dimethyl ammonium chloride (ROCCAL-MC-14--Hilton-Davis). The methylene bis thiocyanate or combination of microbicides is utilized for shipment or make up concentration in a weight percentile of 5-20%; a preferred percentile of 5-10%; and an optimum percentile of about 10%, based upon the xanthan carrier in water. The critical microbicide particle size, which is slightly greater than colloidal, is in the broad range 0.8-150 microns, with a preferred average particle size of 1-45 microns.
REFERENCES:
patent: 3507901 (1970-04-01), Matt et al.
patent: 3551133 (1970-12-01), Sprayberry et al.
patent: 3560390 (1971-02-01), Gaines
patent: 3717452 (1973-02-01), Gibsen et al.
Nalco Chemical Company
Premo John G.
Roberts John S.
Turner V. D.
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