VR1 vanilloid receptor antagonists with a iononic substructure

Details VR1 vanilloid receptor antagonists with a iononic substructure VR1 vanilloid receptor antagonists with a iononic substructure

2011-04-05

2011-04-05

Kumar, Shailendra (Department: 1621)

Organic compounds -- part of the class 532-570 series

Organic compounds

Heterocyclic carbon compounds containing a hetero ring...

C514S307000

Reexamination Certificate

active

07919624

ABSTRACT:
The invention provides compounds of formula (I), wherein Y, R, n and X are as defined in the description, a process for their preparation and pharmaceutical compositions containing them. The compounds of formula (I) inhibit the Transient Receptor Potential Vanilloid 1 (TRPV1), which plays a pivotal role in the development of post-inflammatory analgesia, therefore they can be used as analgesic and anti-inflammatory drugs.

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