Electricity: measuring and testing – Particle precession resonance – Using a nuclear resonance spectrometer system
Patent
1988-08-10
1990-01-09
Tokar, Michael J.
Electricity: measuring and testing
Particle precession resonance
Using a nuclear resonance spectrometer system
324307, G01R 3320
Patent
active
048930806
ABSTRACT:
The measurement of localized spectra by means of stimulated echoes is known per se. Using three 90.degree. pulses, stimulated echoes are then generated; these pulses are selective or not. However, this technique it is not suitable for measuring good proton spectra of metabolites because the response of the non-bound protons is much greater than the response of the bound protons. In accordance with the invention, a fourth (spatially selective) 180.degree. refocusing pulse is added to a pulse sequence consisting of a 90.degree. non-spatially selective but frequency-selective pulse and two subsequent 90.degree. spatially selective pulses. Thus, a refocused stimulated echo is generated in which the response of the non-bound protons is suppressed and which contains only signals from the chemically bound protons. The proposed methods are particularly suitable for measurements on lactate because of the excellent spectral editing properties.
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Den Boef Johannes H.
Den Hollander Jan A.
Luyten Peter R.
Van Vaals Johannes J.
Briody Thomas A.
Haken Jack E.
Slobod Jack D.
Tokar Michael J.
U.S. Philips Corporation
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