Chemistry: molecular biology and microbiology – Measuring or testing process involving enzymes or... – Involving antigen-antibody binding – specific binding protein...
Reexamination Certificate
2008-07-29
2008-07-29
Ulm, John D (Department: 1649)
Chemistry: molecular biology and microbiology
Measuring or testing process involving enzymes or...
Involving antigen-antibody binding, specific binding protein...
C436S501000, C530S350000
Reexamination Certificate
active
07405052
ABSTRACT:
A composition of matter suitable for use in identifying chemical compounds that bind to voltage-dependent ion channel proteins, the composition comprising a screening protein that comprises an ion channel voltage sensor domain of the ion channel protein immobilized on a solid support.
REFERENCES:
patent: 5368712 (1994-11-01), Tomich et al.
patent: 2002/0187524 (2002-12-01), Curtis
patent: 2005/0101767 (2005-05-01), Clapham et al.
patent: 2005/0267009 (2005-12-01), Deagle
Bezanilla, Francisco, Physiological Reviews, 80(2)555-592, Apr. 2000.
Lee-Sy et al., PNAS 102(43)15441-15446.
Ruta-V et al., Nature 422(180-184)2003.
Kawarabayasi-Y. et al., DNA Research 6(83-101)1999.
Voges-D. et al., FEBS Letters, 429(104-108)1998.
Ruta, Vanessa, et al., “Functional analysis of an archaebacterial voltage-dependent K+channel”,Natureadvance online publication Mar. 2, 2003 (doi:10.1038
ature01473).
Schoenherr, et al., “Conformational Switch Between Slow and Fast Gating Modes: Allosteric Regulation of Voltage Sensor Mobility in the EAG K+ Channel”,Neuron2002, 35(5):935-949.
Jiang Youxing
MacKinnon Alice Lee
MacKinnon Roderick
Ruta Vanessa
Feit Irving N.
Hoffmann & Baron , LLP
The Rockefeller University
Ulm John D
LandOfFree
Voltage sensor domains of voltage-dependent ion channel... does not yet have a rating. At this time, there are no reviews or comments for this patent.
If you have personal experience with Voltage sensor domains of voltage-dependent ion channel..., we encourage you to share that experience with our LandOfFree.com community. Your opinion is very important and Voltage sensor domains of voltage-dependent ion channel... will most certainly appreciate the feedback.
Profile ID: LFUS-PAI-O-2803924