Voltage-gated potassium channel gene, KV1.7, vectors and host ce

Chemistry: molecular biology and microbiology – Micro-organism – tissue cell culture or enzyme using process... – Recombinant dna technique included in method of making a...

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536 235, 4353201, 4352402, 4352523, 43525411, C12N 1512, C12N 1563, C12N 510, C12N 121

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055590098

ABSTRACT:
This disclosure relates to the identification of a new voltage-gated potassium channel gene, Kv1.7, which is expressed in pancreatic .beta.-cells. The invention utilizes this new potassium channel for assays designed to identify extrinsic materials with the ability to modulate said channel for the development of therapeutics effective in the treatment of non-insulin-dependent diabetes mellitus.

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