Voltage-gated calcium channel and antisense oligonucleotides the

Chemistry: molecular biology and microbiology – Animal cell – per se ; composition thereof; process of... – Method of regulating cell metabolism or physiology

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435 6, 536 235, 536 243, 536 2431, 536 2433, 536 245, C12N 510, C07H 2100, C12Q 168

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058245502

ABSTRACT:
An antisense oligonucleotide of 10 to 35 nucleotides in length that can hybridize with a region of the .alpha..sub.1 subunit of the SA-Cat channel gene DNA or mRNA is provided, together with pharmaceutical compositions containing and methods utilizing such antisense oligonucleotide.

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