Organic compounds -- part of the class 532-570 series – Organic compounds – Carbohydrates or derivatives
Reexamination Certificate
2008-07-08
2008-07-08
Lukton, David (Department: 1654)
Organic compounds -- part of the class 532-570 series
Organic compounds
Carbohydrates or derivatives
C536S001110, C536S004100, C536S018500
Reexamination Certificate
active
11474671
ABSTRACT:
A solid phase synthetic method is disclosed in which the usual solid phase synthetic steps are carried out and the spent solid phase support is reacted to form a volatilizable compound upon cleavage of the reaction product from the solid phase support. The cleaved product is then separated from the volatile compound by volatilization of that compound. Exemplary solid supports that form a volatilizable compound are also disclosed.
REFERENCES:
patent: 3901872 (1975-08-01), McKinley et al.
patent: 4623716 (1986-11-01), Stevenson et al.
patent: 4631270 (1986-12-01), Yankeelov, Jr. et al.
patent: 4761401 (1988-08-01), Couchman et al.
patent: 5037882 (1991-08-01), Steel
patent: 5188733 (1993-02-01), Wang et al.
patent: 5369017 (1994-11-01), Wong et al.
patent: 5455227 (1995-10-01), Curstedt et al.
patent: 5513024 (1996-04-01), Kang
patent: 5552471 (1996-09-01), Woo et al.
patent: 5859277 (1999-01-01), Whitlock et al.
patent: 5922840 (1999-07-01), Tomich et al.
patent: 6008321 (1999-12-01), Li et al.
patent: 6538117 (2003-03-01), Wong et al.
patent: 6723843 (2004-04-01), Toth et al.
patent: 6765089 (2004-07-01), Toth et al.
patent: WO 98/22197 (1998-05-01), None
patent: WO 00/46238 (2000-08-01), None
Zheng, J. Org. Chem. 63, 1126-30, 1998.
Seeberger, Peter H., Journal of Carbohydrate Chemistry (2002), 21(7-9), 613-643.
Seeberger, P. H., J. Am. Chem. Soc. 1997; 119(42); 10064-10072.
Seeberger P. H., Acc. Chem. Res. 31, 685-695 1998.
Merrifield, J. Am. Chem. Soc., 85:2149-2154 (1963).
Atherton, et al., J. Am. Chem. Soc., 97:6584-6585 (1975).
Parr, et al., Liebigs Ann. Chem., pp. 655-666 (1974).
Fodor, et al., Science, 251:767-773 (1991).
Plunkett, et al., J. Org. Chem. 60:6006-6007 (1995).
Houghten, et al., Proc. Natl. Acad. Sci. USA, 82:5131-5135 (1985).
Houghten, et al., Nature, 354:84-86 (1991).
Pinella, et al., BioTechniques, 13:901-905 (1992).
Ostresh, et al., Proc. Natl. Acad. Sci. USA, 91:11138-11142 (1994).
Dooley, et al., Science, 266:2019-2022 (1994).
Eichler, et al., Molecular Medicine Today, 1:174-180 (1995).
Atherton, et al., Perspectives in Peptide Chemistry, pp. 101-117 (1981).
Bayer, et al., Tetrahedron Letters, 51:4503-4505 (1970).
Parr, et al., Angew. Chem. Internat. Edit, 11:314-315 (1972).
Danishefsky, et al., Science, 260:1307-1309 (1993).
Wong, et al., J. Am. Chem. Soc., 115:5893:5901 (1993).
Bianco, et al., J. Am. Chem. Soc., 119:7550-7554 (1997).
Houghten Richard A.
Moran Michael J.
Pascal Jeanick H.
Lukton David
Mixture Sciences, Inc.
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