Drug – bio-affecting and body treating compositions – Designated organic active ingredient containing – Having -c- – wherein x is chalcogen – bonded directly to...
Patent
1997-12-22
2000-01-04
Raymond, Richard L.
Drug, bio-affecting and body treating compositions
Designated organic active ingredient containing
Having -c-, wherein x is chalcogen, bonded directly to...
514258, 514260, 514261, 514266, 514272, 514303, 514367, 514375, 514379, 514381, 514382, 514383, 514388, 514405, 514414, 514416, 514418, 514443, 514469, 514480, 514618, 514621, 544256, 544276, 544278, 544280, 544284, 544286, 544297, 544330, 544331, 544332, 546118, 546141, 548152, 548180, 548251, 548277, 5483027, 5483031, 5483037, 5483051, 5483071, 5483111, 5483121, 5483315, 5483015, 5483626, 5483648, 548465, 548467, 548472, 548487, 549 55, 549467, 560 28, 564162, 564169, A61K 3147, G07D21724
Patent
active
060110457
ABSTRACT:
The present invention relates to compounds of the formula I
REFERENCES:
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M.A. Horton et al., "Arg-Gly-Asp (RGD) Peptides and the Anti-Vitronectin Receptor Antibody 23C6 Inhibit Dentine Resorption and Cell spreading by Osteoclasts," Experimental Cell Research, 195, 1991, pp. 368-375.
M. Friedlander et al., "Definition of Two Angiogenic Pathways by Distinct .alpha..sub.v Integrins," Science, vol. 270, Dec. 1995, p. 1500-1502.
V. Engleman et al., "A Peptidomimetic Antagonist of the .alpha..sub.v .beta..sub.3 Integrin Inhibits Bone Resorption In Vitro and Prevents Osteoporosis In Vivo," J. Clin. Invest., vol. 99, No. 9, May 1997, p. 2284-2292.
Carniato Denis
Gadek Thomas Richard
Knolle Jochen
Lefrancois Jean-Michel
McDowell Robert
Genentech Inc.
Hoechst Aktiengesellschaft
Raymond Richard L.
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