Vitro bleeding time determination

Chemistry: analytical and immunological testing – Clotting or clotting factor level tests

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436165, 436809, 422 58, 422 73, 73 641, G01N 1104, G01N 3348

Patent

active

050894226

ABSTRACT:
An apparatus and method for in vitro bleeding time determination. Blood is placed in a tube having a window covered with a clot promoting material having a slit. The time required before blood stops flowing through the slit is recorded, and is the bleeding time. It is preferred that the clot-promoting material be nylon fabric impregnated with collagen and blood clot promoting proteins.

REFERENCES:
patent: 4599219 (1986-07-01), Cooper et al.
patent: 4604894 (1986-08-01), Kratzer et al.
D. Brubaker, "An In Vitro Bleeding Time Test", Am. J. Clin. Path., 91,422 (1989).
M. A. A. Kratzer et al, "Streamline Pattern and Velocity Components of Flow in a Model of a Branching Coronary Vessel", Microvascular Res, 31,250 (1986).
Von Der Goltz advertisement entitled "In Vitro Blutungzeit."
"A Protocol for Cryoprecipate Production", Transfusion, Burka et al., vol. 15, No. 4, 1975 (p. 307).

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