Organic compounds -- part of the class 532-570 series – Organic compounds – 9,10-seco-cyclopentanohydrophenanthrene ring system or...
Patent
1991-08-27
1993-05-11
Cintins, Marianne M.
Organic compounds -- part of the class 532-570 series
Organic compounds
9,10-seco-cyclopentanohydrophenanthrene ring system or...
C07J 900
Patent
active
052102378
ABSTRACT:
Vitamin D.sub.3 analogues of the formula: ##STR1## wherein R.sup.1 is hydrogen atom and R.sup.2 is hydroxy, or R.sup.1 is hydroxy and R.sup.2 is hydrogen atom, X is hydrogen atom, hydroxy or a hydroxy protected by a hydroxy-protecting group, and R.sup.3 is hydrogen atom or a hydroxy-protecting group, which have vitamin D.sub.3 -like activities such as activity of controlling calcium metabolism and tumor cell differentiation-inducing activity.
REFERENCES:
patent: 4853378 (1989-08-01), Hamma et al.
patent: 4973721 (1990-11-01), Ikekawa
K. W. Colston et al, "Lancet", Jan. 28, 1988, 1989.
Ikekawa Nobuo
Iseki Katsuhiko
Kobayashi Yoshiro
Nagai Tadabumi
Tanaka Yoko
Cintins Marianne M.
Cook Rebecca
Daikin Industries Ltd.
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