Vitamin D receptor modulators

Drug – bio-affecting and body treating compositions – Designated organic active ingredient containing – Having -c- – wherein x is chalcogen – bonded directly to...

Reexamination Certificate

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Details

C548S217000, C548S224000, C548S237000

Reexamination Certificate

active

07659296

ABSTRACT:
The present invention relates to novel, non-secosteroidal, phenyl-benzoxazole compounds of Formula (I) wherein the variables R, R′, RP, RP3, LP1, LP2, ZP, RB, RB′, LXBand ZXBare as hereinafter defined, their preparation, pharmaceutical compositions, and methods of use.

REFERENCES:
patent: 2006/0094778 (2006-05-01), Nagpal et al.
patent: 2006/0135484 (2006-06-01), Nagpal et al.
patent: 2006/0287536 (2006-12-01), Dahnke et al.
patent: 2006/0293385 (2006-12-01), Gajewski et al.
patent: 2007/0105951 (2007-05-01), Gajewski et al.
patent: 2007/0106095 (2007-05-01), Lu et al.
patent: 2007/0149810 (2007-06-01), Lu et al.
patent: WO 03/101978 (2003-12-01), None
patent: WO 2004/048309 (2004-06-01), None
patent: WO 2005/051893 (2005-06-01), None
patent: WO 2005/051938 (2005-06-01), None
patent: WO 2006/069153 (2006-06-01), None
Nagpal, S. et al. “Vitamin D Analogs: Mechanism of Action of Therapeutic Applications”,Curr. Med. Chem. 2001, 1661-1679, vol. 8.
Bouillon R., et al. Structure-Function Relationships in the Vitamin D Endocrine System, Endocrine Rev. 1995, 200-257, vol. 16.
Swann et al. “Rational Design of Vitamin D3 Analogues Which Selectively Restore Activity to a Vitamin D Receptor Mutant Associated with Rickets”Org. Lett.2002, p. 1863-3866 vol. 4.
Swann et al. “Structure-Based Design of Selective Agonists for a Rickets-Associated Mutant of the Vitamin D Receptor”J. Am. Chem. Soc.2002 13795-13805, vol. 124.

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