Vitamin D derivatives with carbo-or heterocyclic...

Organic compounds -- part of the class 532-570 series – Organic compounds – 9,10-seco-cyclopentanohydrophenanthrene ring system or...

Reexamination Certificate

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C514S167000

Reexamination Certificate

active

10658326

ABSTRACT:
Compounds of Formula I,wherein Y1, Y2, R1–R6, Q and Z are as defined herein, are vitamin D derivatives. These compounds are useful for, e.g., the treatment hyperprolifierative diseases of the skin, tumor diseases and precancerous stages, auto-immune diseases, rejection reactions in the case of autologous, allogenic or xenogenic transplants, AIDS, atopic skin conditions, secondary hyperparathyroidism, renal osteodystrophia, senile and postmenopausal osteoporosis, diabetes mellitus type II, degenerative diseases of the peripheral and central nervous system, hypercalcemias, granulomatous diseases, paraneoplastic hypercalcemias, hypercalcemias in hyperparathyroidism, hirsutism, ateriosclerosis, and/or inflammatory diseases.

REFERENCES:
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patent: 6124276 (2000-09-01), Miyamoto et al.
patent: 6127559 (2000-10-01), DeLuca et al.
patent: 6479538 (2002-11-01), Reddy
Glenville Jones et al., TEM, (Elsevier Science Publishing COo) vol. 4, No. 9, 1993, pp. 297-303.

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