Vitamin D derivatives

Details Vitamin D derivatives Vitamin D derivatives

2006-07-11

2006-07-11

Badio, Barbara P. (Department: 1617)

Drug, bio-affecting and body treating compositions

Designated organic active ingredient containing

9,10-seco- cyclopentanohydrophenanthrene ring system doai

C552S653000, C514S863000

Reexamination Certificate

active

07074777

ABSTRACT:
The object of the present invention is to provide a vitamin D derivative exhibiting excellent physiological activity as medicines, in particular as therapeutic agents for skin disease including psoriasis, and having decreased hypercalcemic activity.The present invention provides vitamin D derivatives represented by the general Formula (1):whereinin Formula (1), X is oxygen or sulfur;R1is hydrogen or Formula (2)R2is hydrogen or alkyl;R3and R4are hydrogen or alkyl or R3and R4together form a double bond between the 16- and 17-positions;R5is hydrogen or —OR13in which R13is hydrogen or a protecting group; andR6is hydrogen or a protecting group.

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