Chemistry of carbon compounds – Miscellaneous organic carbon compounds – C-metal
Patent
1988-01-20
1989-02-14
Lone, Werren B.
Chemistry of carbon compounds
Miscellaneous organic carbon compounds
C-metal
C07J 900
Patent
active
048045020
ABSTRACT:
Compounds of the formula ##STR1## wherein R.sub.1 is hydrogen or hydroxy and R.sub.2 is hydrogen or fluorine are described. The compounds of formula I are useful as agents in the treatment of disease states characterized by metabolic calcium deficiencies. Examplary of such disease states are osteoporosis and renal osteodystrophy.
REFERENCES:
patent: 4358406 (1982-11-01), Deluca et al.
patent: 4521410 (1985-06-01), Holich et al.
patent: 4689180 (1987-08-01), Deluca et al.
Baggiolini Enrico G.
Partridge John J.
Shiuey Shian-Jan
Truitt Gary A.
Uskokovic Milan R.
Boxer Matthew
Hoffmann-La Roche Inc.
Leon Bernard S.
Lone Werren B.
Saxe Jon S.
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