Vitamin B.sub.12 derivative suitable for radiolabeling

Details Vitamin B.sub.12 derivative suitable for radiolabeling Vitamin B.sub.12 derivative suitable for radiolabeling

1978-05-30

1980-06-24

Brown, Johnnie R.

Organic compounds -- part of the class 532-570 series

Organic compounds

Carbohydrates or derivatives

23230R, 424 15, 424 12, A61K 3168, C07H 2300

Patent

active

042096146

ABSTRACT:
Radiolabeled vitamin B.sub.12 derivatives having the formula ##STR1## wherein R is hydrogen or alkyl of 1 to 3 carbon atoms; n is 0, 1, 2, 3 or 4; and the asterisk (*) indicates tagging with a radioisotope, are useful as tracers in radioassays.

REFERENCES:
patent: 3459855 (1969-08-01), Thuillier
patent: 3981863 (1976-09-01), Niswender et al.
Kim et al. "Jour. Nucl. Med.", vol. 17, No. 8, 1976, pp. 737-739.
Endres et al. "Clin. Chem.", vol. 24, No. 3, 1978, pp. 460-465.

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