Viscoelastic solution

Details Viscoelastic solution Viscoelastic solution

1989-11-13

1994-11-22

Brown, Johnnie R.

Drug, bio-affecting and body treating compositions

Designated organic active ingredient containing

Carbohydrate doai

514 54, 514 59, 514912, A61K 31715

Patent

active

053669649

ABSTRACT:
A viscoelastic solution including a buffered solution, 0.01-10% chondroitin sulfate, 0.01-10% hydroxypropyl methylcellulose, and 0.01-10% sodium hyaluronate, pH adjusted to 6.0-8.0 at a osmolarity between 200-400 mOsmol/L. The buffered solution can be HEPES buffered minimal essential medium (MEM), phosphate buffered saline (PBS), or buffered balanced salt solution. A cell growth factor or cell growth supplement can also be included in the solution.

REFERENCES:
patent: 4713375 (1987-12-01), Lindstrom et al.
patent: 4886786 (1989-12-01), Lindstrom et al.
patent: 5013714 (1991-05-01), Lindstrom et al.
Couch et al., "Mitotic Activity of Corneal Endothelial Cells in Organ Culture with Recombinant Human Epidermal Growth Factor", Ophthalmology, Jan., 1987, vol. 94, No. 1, pp. 1-4.

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