Viscoelastic solution

Details Viscoelastic solution Viscoelastic solution

1991-05-03

1993-04-20

Cashion, Jr., Merrell C.

Drug, bio-affecting and body treating compositions

Designated organic active ingredient containing

Peptide containing doai

514 3, 514 12, 514 21, A61K 3700, A61K 3726, A61K 3736

Patent

active

052043258

ABSTRACT:
Viscoelastic solution including a buffered solution, 0.01-8% chondroitin sulfate, 0.1-8% hydroxypropyl methylcellulose, pH adjusted to 6.0-8.0 at a osmolality between 200-400 mOsmol/L. The buffered solution can be HEPES buffered minimum essential media (MEM), phosphate buffer saline (PBS), buffered balanced salt solution, or TC199. A cell growth factor or cell growth supplement is included in the solution.

REFERENCES:
patent: 4713375 (1987-12-01), Lindstrom et al.
patent: 5013714 (1991-05-01), Lindstrom et al.
Skelnik et al., Invest. Ophthalmol. Visual Sci 28 (3 Suppl) 1987, p. 326.
Couch et al., "Mitotic Activity of Corneal Endothelial Cells in Organ Culture with Recombinant Human Epidermal Growth Factor", Ophtalmology, Jan., 1987, vol. 94, No. 1, pp. 1-4.

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